Owen Lane will make his Rugby World Cup debut alongside four of his regional team-mates in the third-place play-off against New Zealand on Friday.
Warren Gatland has made a total of nine changes for the Tokyo clash, as wing Lane, who made a try scoring debut in the warm up clash against Ireland, lines up in an all-Cardiff Blues back three.
The Cardiff Blues academy product missed out on initial selection for Japan, but linked up with the squad as an injury replacement for Josh Navidi.
Summer recruits, Hallam Amos and Josh Adams, start at full back and wing respectively, with the latter looking to seal his place as the tournament's top try scorer. Adams currently leads the charts with six tries to his name and is the only Welsh player to start all games during the campaign.
Tomos Williams has enjoyed an impressive tournament as an impact player from the bench. He has been rewarded for his fine form, and will start a Rugby World Cup game for the first time after being given the nod at scrum half.
Dillon Lewis, who has also been drafted into the starting XV, will wear the number three jersey, and is another Cardiff Blues star to feature in all seven games.
Two Cardiff Blues academy products also feature in the form of Rhys Patchell and Rhys Carré.
The clash will signal the end of Warren Gatland's tenure as Wales' head coach, after a successful period which saw Wales clinch three Grand Slams, four Six Nations titles and two World Cup semi final spots.
WALES TEAM TO PLAY NEW ZEALAND ON FRIDAY NOVEMBER 1:
1. Nicky Smith (Ospreys) (34 Caps)
2. Ken Owens (Scarlets) (72 Caps)
3. Dillon Lewis (Cardiff Blues) (21 Caps)
4. Adam Beard (Ospreys) (19 Caps)
5. Alun Wyn Jones (Ospreys) (133 Caps) (CAPT)
6. Justin Tipuric (Ospreys) (71 Caps)
7. James Davies (Scarlets) (7 Caps)
8. Ross Moriarty (Dragons) (40 Caps)
9. Tomos Williams (Cardiff Blues) (15 Caps)
10. Rhys Patchell (Scarlets) (18 Caps)
11. Josh Adams (Cardiff Blues) (20 Caps)
12. Owen Watkin (Ospreys) (21 Caps)
13. Jonathan Davies (Scarlets) (80 Caps)
14. Owen Lane (Cardiff Blues) (1 Cap)
15. Hallam Amos (Cardiff Blues) (21 Caps)
Replacements:
16. Elliot Dee (Dragons) (27 Caps)
17. Rhys Carre (Saracens) (4 Caps)
18. Wyn Jones (Scarlets) (21 Caps)
19. Jake Ball (Scarlets) (41 Caps)
20. Aaron Shingler (Scarlets) (25 Caps)
21. Gareth Davies (Scarlets) (50 Caps)
22. Dan Biggar (Northampton Saints) (78 Caps)
23. Hadleigh Parkes (Scarlets) (24 Caps)