Foster's Sevens champions Pontypridd will play Cross Keys in the opening round of this year's tournament, which will be held at the BT Sport Cardiff Arms Park on Sunday, August 24.
Runners-up Llandovery face Cardiff in Round 1, while semi-finalists Aberavon and RGC 1404 play Newport and Llanelli respectively.
Bedwas, who lifted the Plate at the inaugural event last summer, have drawn Welsh Students.
The rest of the draw sees newcomers Cardiff Met play SWALEC Championship winners Ebbw Vale, Bridgend face fellow Ospreys club Swansea and Neath play Carmarthen Quins.
Elliot Jones, of Cross Keys said, "We lost twice to Pontypridd at the end of last year, in the Cup final and the Play-Off final and they will be tough opponents here as champions. However, we want to prepare well and have a good crack at this.
"Although we are probably better known for our driving line-out, we have some talented backs too and everything is set up for a great day out for all involved, the fans included."
Rugby World Cup Sevens winner Lee Beach, who has joined Neath from Newport, is looking forward to the challenge.
"Sevens is a fantastic way to develop players and we have a lot of youngsters in our squad so it will be good to see how they get on. We have drawn Carmarthen Quins who have a number of experienced Sevens players in their ranks and I for one hope I won't have to face my former world cup team mate Lee Williams on the day!
"Sevens is a great spectator sport - some of the IRB tournaments like Hong Kong and Wellington are amazing tournaments to be part of - and hopefully more and e Welsh supporters will see that and get behind this event again this year."
Bedwas' Matthew John added: "We won the plate last year, the boys played really well, hopefully we can continue that success. It was great winning the plate but hopefully this time we can qualify for the knock-out rounds of the main competition. Hopefully we can take advantage of the Welsh Students' youth and lack of experience and go from there but they will be fit, that's for sure.
"This tournament is ideal for people who want to go higher in rugby and it's a great shop window for those who want to play more sevens in the future as well. It's a good way to get your name out there for the season to come."
Tickets are on sale now for the day long event at just £10 for adults, £5 for Under 16s and £20 for a family ticket (2 adults, 2 children). To purchase tickets, go to www.wru.co.uk/fosterssevens or call 0333 321 9989 (Ticketmaster) or 02920 230130 (Ticketline).
Tickets are also available to personal callers from the WRU shop, 8 Westgate Street, from Ticketline, 47 Westgate Street and from participant clubs.
Tickets are on sale NOW for our huge opening Guinness Pro 12 fixture of the season against Glasgow Warriors - and we've frozen match ticket prices this season so watching top-class rugby at BT Sport Cardiff Arms Park is affordable to all!
Impressive Cardiff Blues pushed English powerhouse side Leicester Tigers all the way with an hugely encouraging performance as final preparations for the new Guinness PRO12 season continued at Welford Road.