Over 11,500 tickets have already been sold for the game and the Blues are on course to break the 12,198 mark, set when the Blues beat the Scarlets by 19 points to 15, in a hugely entertaining game in September.
Martyn Williams starts for the Blues for the first time this season, having recovered from shoulder injury sustained during the Lions tour of South Africa.
Robin Sowden Taylor picked up a knee injury last weekend in Sale and was not considered for selection.
Xavier Rush returns at Number 8 with Andy Powell now suffering from flu that prevented Rush from playing against Sale.
Scott Morgan and Deiniol Jones start at second row, while Bradley Davies is expected to be fit for selection against Leinster next weekend. Paul Tito has been given the all clear to play but only trained with the team at the latter end of the week and now takes his place on the bench. Gethin Jenkins continues as Captain.
In the backs Gareth Thomas has not recovered from his groin injury but is expected to be fit for selection for next weekend's away match at Leinster. Gareth Cooper starts at Scrumhalf.
There are a small amount of seats left in the Ninian Stand and Grandstand and supporters are advised to purchase tickets as early as possible for this eagerly anticipated fixture.
Tickets for the match are available from all the normal outlets, online at www.cardiffblues.com/tickets , by phone on 0845 345 1400 and in person at the Cardiff City stadium ticket office.
15 Ben Blair 14 Leigh Halfpenny 13 Tom Shanklin 12 Jamie Roberts 11 Tom James 10 Sam Norton-Knight 9 Gareth Cooper
8 Xavier Rush 7 Martyn Williams 6 Sam Warburton 5 Scott Morgan 4 Deiniol Jones 3 Taufa'ao Filise 2 Gareth Williams 1 Gethin Jenkins (c)
16 T Rhys Thomas 17 Gary Powell 18 Paul Tito 19 Ben White 20 Richie Rees 21 Ceri Sweeney 22 Richard Mustoe