Blues prop Gethin Jenkins has withdrawn from the Wales starting line up for the RBS 6 Nations clash with England at Twickenham on Saturday after failing a fitness test this afternoon (Thursday) on a calf problem picked up in training.
Jenkins will be replaced in the starting line-up by prop Paul James and the uncapped Rhondda-born Saracens propand former Cardiff Blue Rhys Gill takes up the spot vacated by James on the bench.
"Paul James has been one of the form props in the Welsh regions so far this season and we are confident he will be a more than able
deputy for Gethin," said Wales head coach Warren Gatland.
"Obviously it's not ideal for us to lose Gethin at this stage and we wish him a speedy recovery."
Jenkins will remain in the Wales camp and his injury will be re-assessed next week.
Thank Blues it's Friday! The weekend will be starting HERE on Friday night as Cardiff Blues tackle Ulster in the Guinness PRO12 at BT Sport Cardiff Arms Park - and we want you to be our guest at our big match day party!
Let the Games Begin! Cardiff Blues launch the Guinness PRO12 season on home soil this Sunday afternoon against Glasgow Warriors (kick-off 4pm) - and we are going to make it a double celebration as we also recognise the achievements of Team Wales!
As well as the half marathon on Sunday (October 5), the 2014 Lloyds Bank Cardiff Half Marathon also sees the return of the action-packed Lloyds Bank Festival of Running to Cardiff's Civic Centre on Saturday (October 4, starting 11am) where you can see our mascot Bruiser the Bear in action!
Second half tries from Dan Tuohy and Ian Humphreys saw Ulster claim the Friday night points on offer as Cardiff Blues suffered a 26-9 defeat to the impressive Irish province at BT Sport Cardiff Arms Park.
Clinical Glasgow Warriors produced a devastating final 20 minutes to secure the points on Super Sunday and consign battling Cardiff Blues to a 33-12 defeat in the Guinness PRO12 opener at BT Sport Cardiff Arms Park.