The inclusion of a clause in this season's Tournament Rules requiring any games that have an impact on qualification for the Play-Offs to kick-off the same day and time means that two of the games, Cardiff Blues v Munster and Leinster v Edinburgh, will be played simultaneously.
Three teams have already qualified for the inaugural Magners League Play-Offs, Leinster, Ospreys and Glasgow Warriors, whilst three further teams, Munster, Cardiff Blues and Edinburgh are vying the fourth and final qualifying spot.
The full Round 18 fixtures are as follows:
Friday 7 May
7.05pm Scarlets v Glasgow Warriors at Parc y Scarlets
7.30 pm Ulster v Connacht at Ravenhill, live on Setanta Ireland
Sunday 9 May
6.15pm Cardiff Blues v Munster at Cardiff City Stadium, live on S4C and Setanta 1
6.15pm Leinster v Edinburgh at RDS Dublin, live on Setanta Ireland
Ospreys v Newport Gwent Dragons TBC
Tickets for the Cardiff Blues v Munster match are available now online or from the ticket office on 0845 345 1400
Magners League Play-Off semi finals will take place the weekend of 14/15/16 May
The Magners League Grand Final is on Saturday 29 May, kick-off 6.30pm.
All fixtures and venues subject to change.