With the Blues North sitting comfortably on top of the table but with a night off tonight, it's the turn of the South to try and make the headlines and to maintain the lead set by the region's other three sides.
Because not only are the North in top form at under 16 level, the under 18s and under 20s are currently at the top of their respective leagues. the South XV will be looking to inflict a third defeat of the season on an Ospreys side who went down 8-7 to the North last time out.
Meanwhile home advantage should help the Scarlets to counter what will be a fierce challenge from a Dragons side still smarting from their 10-0 home defeat at the hands of Blues South.
Blues South: Josh Davies, Nathan Hoosan, Dylan Jones, Edward Doe, Loren Quick, Ross Wardle, Tom Rowlands, Gus Davies, Keith Machunga, Joe Poole (c), Adam Thompson, Daniel Jones, Alex Phillips, Ashley Rowley, James Llewellyn
Subs Dan Fish, Gareth Llewellyn, Scott Gunter, Owain Poole, Owain Thomas, Michael Walentine, Stuart Edbrooke