The game, which was originally scheduled for Rodney Parade, was reversed after Newport declared their home pitch unplayable due to heavy rain during the day.
And having doen that, the Blues made the most ofhome advantage as they raced into a 42-0 half time lead before making wholesale changes.
Centre Tom Cooper got the scoreboard ticking with his side's first of eight tries and by half time they were comfortably ahead with James Egan, Luke Ford (2), Aaron Fowler and Patrick Palmer adding further tries.
Daniel Matthews and no.8 Mathew Larsen added tries after the interval and with Kristian Baller kicking seven conversions, the Blues were home and dry.
Dragons hooker Ben Roberts grabbed a consolation for the Dratons with Davud Langdon converting, but the visitors were outplayed and outmuscled for much of the contest with the Blues showing why they have a 100 per cent record at this level this season.
For the Blues, Ford, the son of former Wales wing Steve, was outstanding with high performance manager Gafyn Cooper saying, "We have made big strides this season as a region and this was another excellent all-round performance.
"The confidence is obviously there and the likes of Luke are thriving on that."