In the forwards Gethin Jenkins and Gary Powell come in and will start in the front row. Taufaao Filise moves to the bench and is joined by Rhys Shellard, Ed Fairhurst, Dai Flanagan and Dafydd Hewitt as Marc Stcherbina has still not recovered from his calf injury.
Mark Lewis also suffered grade 2 medial ligament damage to his left knee in the match against Munster which is expected to keep him out of action for between 4 to 6 weeks
Tickets for the match against the Ospreys must be purchased by 12.00 mid day on Saturday. There are less than 1,000 north terrace tickets available and stand tickets are sold out. The Ticket Office will be open until 7.00pm on Friday and will re-open at 8.30am on Saturday to cope with demand.
Supporters can purchase their tickets by calling the ticket office on 029 2030 2030 or purchase online until 9.00am Saturday on Prices start at £4 for juniors, £12 concessions and £15 for adults.
Team Nick Macleod, Ben Blair, Jamie Robinson, Tom Shanklin, Chris Czekaj, Nick Robinson, Mike Phillips, Xavier Rush (C), Martyn Williams, Scott Morgan, Deiniol Jones, Bradley Davies, Gary Powell, T Rhys Thomas, Gethin Jenkins
Replacements: Taufaao Filise, Gareth Williams, Ben White, Rhys Shellard, Ed Fairhurst, Dai Flannagan, Dafydd Hewitt